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Abstract
The global burden of HIV/AIDS, particularly in Sub-Saharan Africa, is compounded by malnutrition, which accelerates disease progression despite advancements in antiretroviral therapy (ART). This study evaluated the impact of a nutrition education intervention on the nutritional status and clinical indices of people living with HIV/AIDS (PLWHA) at Namong SDA Hospital in Ghana. Sixty PLWHA were randomized into intervention and non-intervention groups. The intervention included individualized nutrition education sessions focused on dietary diversity, macronutrient and micronutrient intake, and the use of locally available foods. Baseline data revealed significant gaps in nutritional knowledge, with 91.7% of participants demonstrating low knowledge about the relationship between nutrition and HIV. Dietary inadequacies were widespread, particularly for iron, zinc, and Vitamin E, with 100% of participants falling below the recommended intake for Vitamin E. Post-intervention results showed significant improvements in dietary practices within the intervention group, with higher mean intakes of protein (47.9 ± 12.8 mg vs. 42.5 ± 12.7 mg), Vitamin C (97.4 ± 31.2 mg vs. 75.6 ± 32.6 mg), and selenium (55.1 ± 21.2 mg vs. 32.8 ± 13.5 mg), though statistical significance was not achieved for most indices. Trends toward improved clinical outcomes, including serum albumin and CD4 counts, were observed but did not reach significance. The findings highlight the potential of culturally tailored nutrition education in addressing nutritional deficiencies and improving dietary practices among PLWHA. Future research should explore the long-term impact of such interventions, integrating supplementation and systemic support to enhance clinical outcomes in resource-limited settings.
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References
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References
Amuna, P., & Zotor, F. B. (2008). Epidemiological and nutrition transition in developing countries: Impact on human health and development. Proceedings of the Nutrition Society, 67(1), 82–90. https://doi.org/10.1017/S0029665108006058
Bhargava, A., & Ravindra, P. (2017). Effects of nutritional education on dietary diversity and food security among people living with HIV/AIDS in India. Nutrition Journal, 16(1), 1–9. https://doi.org/10.1186/s12937-017-0267-9
Fawzi, W. W., Spiegelman, D., & Reddy, P. (2005). The role of nutrition in HIV infection and disease progression. Annual Review of Nutrition, 25(1), 511–538. https://doi.org/10.1146/annurev.nutr.25.050304.092542
Friis, H. (2006). Micronutrients and HIV infection: A review of current evidence. Public Health Nutrition, 9(5), 573–593. https://doi.org/10.1079/PHN2005894
Ghana AIDS Commission. (2020). National HIV and AIDS strategic plan 2021–2025. Retrieved from https://www.ghanaids.gov.gh
Ivers, L. C., Cullen, K. A., Freedberg, K. A., Block, S., Coates, J., & Webb, P. (2009). HIV/AIDS, undernutrition, and food insecurity. Clinical Infectious Diseases, 49(7), 1095–1102. https://doi.org/10.1086/605573
Kotler, D. P., Tierney, A. R., Wang, J., & Pierson, R. N. (2015). Body composition studies in HIV-infected and control subjects. American Journal of Clinical Nutrition, 63(4), 800–804. https://doi.org/10.1093/ajcn/63.4.800
Macallan, D. C. (2005). Nutrition and immune function in HIV infection: Lessons from tuberculosis. British Journal of Nutrition, 93(1), S17–S24. https://doi.org/10.1079/BJN20041343
McDermid, J. M., Weiser, S. D., & Semba, R. D. (2015). Nutritional supplements for improving treatment outcomes in patients with HIV infection. Cochrane Database of Systematic Reviews, 2, CD004536. https://doi.org/10.1002/14651858.CD004536.pub4
Nnyepi, M. S. (2014). The risk of developing malnutrition in people living with HIV/AIDS: Observations from sub-Saharan Africa. Nutrition, 30(10), 983–989. https://doi.org/10.1016/j.nut.2014.02.015
Rawat, R., Kadiyala, S., & McNamara, P. E. (2014). The impact of food assistance on weight gain and disease progression among HIV-infected individuals receiving antiretroviral therapy: Evidence from a literature review. AIDS and Behavior, 18(5), 951–960. https://doi.org/10.1007/s10461-014-0726-y
Ruel-Bergeron, J. C., Stevens, G. A., Sugimoto, J. D., Roos, F. F., Ezzati, M., Black, R. E., & Kraemer, K. (2019). Global update and trends of hidden hunger, 1995–2011: The hidden hunger index. PLOS ONE, 14(2), e0212633. https://doi.org/10.1371/journal.pone.0212633
UNAIDS. (2021). Global HIV & AIDS statistics — Fact sheet. Retrieved from https://www.unaids.org